There's several routes - and as such several ways to play - in Adventure High.
Heroic Path
The Protagonist uses his/her power for good and refuses to enslave anyone. Instead, the Protagonist will focus on stopping Drape from taking over school.
Tempted Hero
During Tempted Hero, the Protagonist has enslaved at least one other character.
Faculty Control
This route focuses on enslaving all teachers. At present time, only Ms. Rack and Dr. Tiff are possible to enslave.
Student Control
This route focuses on enslaving all students in the school. At present time, Val, Sarah, Julia, Cassandra, Ashley and Molly are possible to enslave.
Submissive Slave
If you lose the battle against Cassandra, she'll refer to herself as the Protagonist's Mistress. You can also enslave Sarah to become Cassandra's slave during this route.